Integrated ethylene oxide sterilizer

 

The conventional limit of temperature is generally 44 ℃ ~ 56 ℃, and the most commonly used temperature is 50 ± 3 ℃. However, when the temperature is high enough to make the drug play its maximum role, when the temperature is increased, the bactericidal effect is no longer improved. The determination of sterilization temperature is related to the following conditions: 

1) temperature tolerance of the sterilized product. 

2) Loading capacity and loading mode: the loading capacity is required to be ≤ 80%, without contacting the cabinet wall, and there is no less than 125px gap between the boxes.

3) Thickness, size and bulk density of packaging materials.

Ethylene oxide does not damage the sterilized articles and has strong penetration, so most articles that are not suitable for general sterilization can be sterilized and sterilized with ethylene oxide. For example, electronic instruments, optical instruments, medical devices, fur, cotton, chemical fiber, plastic products, endoscopes, dialyzers and disposable medical supplies. Ethylene oxide is one of the most important low temperature sterilization methods.

The temperature, humidity, concentration of sterilization gas and sterilization time in the sterilization cabinet are all important parameters that affect the sterilization effect. Ethylene oxide is a kind of alkylating agent with strong penetrability. It can use all kinds of packaging materials and can be sterilized in the packaging state. It can kill all kinds of microorganisms (including bacteria, spores, es, fungal spores, etc.) at room temperature. It is suitable for biomedical high molecular materials that are not resistant to high temperature treatment, such as natural rubber, polyethylene, polypropylene, PVC, etc. The ethylene oxide sterilizer consists of a leakproof and explosion-proof bridge cutoff aluminum steel chamber. First, the material temperature and humidity in the chamber are adjusted through the heating (pre-treatment) process, and then further vacuumized, and then the preheated ethylene oxide gas is introduced. Packaging materials must have good permeability to air, steam and ethylene oxide, so that suitable sterilization conditions can be easily achieved. Due to the potential carcinogenicity, mutagenicity and acute toxicity of ethylene oxide, in order to ensure the safety of workers, the atmospheric concentration, chamber temperature and humidity, pressure, ethylene oxide gas concentration and sterilization time should be closely monitored during the sterilization process. The sterilization effect is usually monitored by a biological indicator. It is difficult to control the sterilizer. The whole sterilization process should be carried out under the supervision of skilled personnel. After sterilization, the filtered sterile air shall be introduced and the vacuum air circulation process shall be experienced to remove the residual ethylene oxide safely.